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Section 4.4(b)(i) of Executive Order 14110 directs the Director of the Office of Science and Technology Policy, within 180 days and in consultation with named agency heads, to establish a framework encouraging providers of synthetic nucleic acid sequences to implement comprehensive, scalable and verifiable procurement screening mechanisms, including standards and recommended incentives. Copy claim link
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Supporting evidence: primary · 1 source; Context: primary · 1 source
Provision Required action · provision ID us-eo14110-sec44bi-nucleic-acid-screening-framework Subject version As published in the Federal Register (1 November 2023) · Published 2023-11-01 · Effective date not established Date 2023-11-01 · publication Scope and limits States what the order directs; it does not establish that the framework was produced, nor impose any duty on a provider. The order's own criteria for identifying sequences that could pose a risk, in subparagraph (A), and its direction on screening methodologies, in subparagraph (B), are not recorded. The dataset already holds this order's Sec. 3(k) definition and Sec. 4.2 reporting provisions; Sec. 4.4 was not recorded there. Only the policy-level direction is cited. The order's subparagraphs on identifying biological sequences that could pose a risk and on screening methodologies are technical and were excluded.
The evidence 02 primary source Supports the claim
Executive Order 14110 of October 30, 2023: Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence (88 FR 75191) ↗ The White House · 2023-11-01
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Source excerpt “shall establish a framework, incorporating, as appropriate, existing United States Government guidance, to encourage providers of synthetic nucleic acid sequences to implement comprehensive, scalable, and verifiable synthetic nucleic acid procurement screening mechanisms, including standards and recommended incentives” Location in source Sec. 4.4(b)(i), 88 FR 75201
How it was read Retrieved directly from the publisher
Machine-checked · 2026-10-30
Source details and check notes Authors The White House Version Retrieved on 2026-10-27 (SHA-256 46739dfc1af256961458d3b73fa4d6f4b447b38eaa72efd80966463818be68ab). Federal Register print of 1 November 2023, Vol. 88, No. 210, pp. 75191–75226, FR Doc. 2023-24283. The PDF text layer renders superscript exponents inline (10^26 appears as "1026"); quotes stop before such numbers. Publisher as printed on the inspected expression: Federal Register (Office of the Federal Register, National Archives) via govinfo.gov. Canonical address Open the canonical source ↗ Accessed 2026-10-27 Language English (en) Attribution The White House, “Executive Order 14110 of October 30, 2023: Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence (88 FR 75191)”, 2023-11-01. Reuse No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution. Check notes Candidate pack passage, AI and biosecurity (research/ai-bio). The quotation (37 words) matched the text retrieved for the candidate pack on 2026-10-28 and again at admission on 2026-10-30, in a fresh retrieval whose SHA-256 equals the pack’s. Matching ignored differences of whitespace, case, quotation marks, dashes and Unicode compatibility forms, so the source’s typography can differ. The subsection opens 'Within 180 days of the date of this order, the Director of OSTP, in consultation with' a list of agency heads. No human editorial review. primary source Context only
Executive Order 14110 of October 30, 2023: Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence (88 FR 75191) ↗ The White House · 2023-11-01
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Source excerpt “To reduce the risk of misuse of synthetic nucleic acids, which could be substantially increased by AI's capabilities in this area, and improve biosecurity measures for the nucleic acid synthesis industry” Location in source Sec. 4.4(b), opening words, 88 FR 75201
How it was read Retrieved directly from the publisher
Machine-checked · 2026-10-30
Source details and check notes Authors The White House Version Retrieved on 2026-10-27 (SHA-256 46739dfc1af256961458d3b73fa4d6f4b447b38eaa72efd80966463818be68ab). Federal Register print of 1 November 2023, Vol. 88, No. 210, pp. 75191–75226, FR Doc. 2023-24283. The PDF text layer renders superscript exponents inline (10^26 appears as "1026"); quotes stop before such numbers. Publisher as printed on the inspected expression: Federal Register (Office of the Federal Register, National Archives) via govinfo.gov. Canonical address Open the canonical source ↗ Accessed 2026-10-27 Language English (en) Attribution The White House, “Executive Order 14110 of October 30, 2023: Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence (88 FR 75191)”, 2023-11-01. Reuse No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution. Check notes Candidate pack passage, AI and biosecurity (research/ai-bio). The quotation (31 words) matched the text retrieved for the candidate pack on 2026-10-28 and again at admission on 2026-10-30, in a fresh retrieval whose SHA-256 equals the pack’s. Matching ignored differences of whitespace, case, quotation marks, dashes and Unicode compatibility forms, so the source’s typography can differ. The order's own stated reason for the subsection, which ties synthesis screening to AI. Recorded as the order's statement, not as a finding about AI capabilities. No human editorial review. Status and meaning Editorial status. Not reviewed by an editor . An exploratory record that no editor has accepted. This status does not say whether a person has read any linked passage. Each evidence record above shows how it was checked.
Relation. An exact framework edition, or another document with an exact expression, states one provision: a capability threshold or risk level and its trigger, a required safeguard or action, a decision authority (who decides, recommends, can overrule or is informed), a stated exception, or another statement of its content, such as a licence term or a prospectus statement. The passage records what the document says, not implementation, compliance or effectiveness. Provisions with the same key align across editions of one family.
Date. Provision as the edition states it, dated by the Federal Register publication of 1 November 2023; the order is signed 30 October 2023. Executive Order 14110 was revoked by Executive Order 14148 of 20 January 2025.
Record ID ab-scr-eo14110-sec44b-ostp-framework