Section 4(b) of Executive Order 14292 directs the Director of the Office of Science and Technology Policy, within 90 days, to revise or replace the 2024 Framework for Nucleic Acid Synthesis Screening, directs the heads of all agencies that fund life-science research to ensure that synthetic nucleic acid procurement is conducted through providers or manufacturers that adhere to the updated framework, and states that the framework shall be reviewed and revised at least every four years.

One recorded claim. The claim panel gives its qualification, the source passages with their place in each source, and how it was checked.