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The 2010 notice states that the final Guidance is directed to all providers of synthetic double-stranded DNA, the recommendations of the draft Guidance having been directed to 'commercial' providers. Copy claim link
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Machine-checked, not reviewed by an editor Stated in source Supported
Supporting evidence: primary · 1 source
Provision Threshold or trigger · provision ID us-hhs-screening-guidance-2010-addressees Subject version As published in the Federal Register of 13 October 2010 (75 FR 62820) · Published 2010-10-13 · Effective 2010-10-13 Date 2010-10-13 · publication Scope and limits Records whom the notice says the final Guidance is directed to, and the change it states from the draft. It is not a finding that any provider, commercial or otherwise, screened an order, and the notice's further remark that 'orders' does not necessarily imply a commercial transaction is not recorded as a separate provision. Split under the one-claim-per-edge rule from recorded separately. The provision kind 'threshold' is the kind the dataset uses for a definition that decides who is covered; see openQuestions.
The evidence 01 primary source Supports the claim
Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA (75 FR 62820) ↗ Federal Register (Office of the Federal Register, National Archives) via govinfo.gov · Publication date unknown
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Source excerpt “the final Guidance is directed to all providers of synthetic dsDNA” Location in source Response to comments on scope, 75 FR 62823
How it was read Retrieved directly from the publisher
Machine-checked · 2026-10-30
Source details and check notes Authors Federal Register (Office of the Federal Register, National Archives) via govinfo.gov Version Retrieved for the candidate pack on 2026-10-28 (SHA-256 d3bfd95a1e3ae4d212505081166f0f8bb7475845e225ae643e6d4a03a93b7e56). Federal Register print of 13 October 2010, Vol. 75, No. 197, pp. 62820-62832, FR Doc. 2010-25728. The notice publishes the final Guidance in full, after the comment responses. Retrieved again at admission on 2026-10-30 (SHA-256 d3bfd95a1e3ae4d212505081166f0f8bb7475845e225ae643e6d4a03a93b7e56, the same bytes). Canonical address Open the canonical source ↗ Accessed 2026-10-28 Language English (en) Attribution Federal Register (Office of the Federal Register, National Archives) via govinfo.gov, “Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA (75 FR 62820)”. Reuse No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution. Check notes Candidate pack passage, AI and biosecurity (research/ai-bio). The quotation (11 words) matched the text retrieved for the candidate pack on 2026-10-28 and again at admission on 2026-10-30, in a fresh retrieval whose SHA-256 equals the pack’s. Matching ignored differences of whitespace, case, quotation marks, dashes and Unicode compatibility forms, so the source’s typography can differ. The passage follows comments that the earlier draft had been directed to commercial providers; the notice adds that 'orders' does not necessarily imply a commercial transaction. A cross-family machine check (2026-10-30, item 54) re-read the record’s sources and found full support. No human editorial review. Status and meaning Editorial status. Not reviewed by an editor . An exploratory record that no editor has accepted. This status does not say whether a person has read any linked passage. Each evidence record above shows how it was checked.
Relation. An exact framework edition, or another document with an exact expression, states one provision: a capability threshold or risk level and its trigger, a required safeguard or action, a decision authority (who decides, recommends, can overrule or is informed), a stated exception, or another statement of its content, such as a licence term or a prospectus statement. The passage records what the document says, not implementation, compliance or effectiveness. Provisions with the same key align across editions of one family.
Date. Provision as the 2010 expression states it, dated by its publication in the Federal Register of 13 October 2010.
Record ID ab-scr-hhs-2010-all-providers-addressees