{"entities":[{"id":"aib-doc-mullard-2021","name":"What does AlphaFold mean for drug discovery?","type":"document","subtype":"Journal article","description":"Nature Reviews Drug Discovery 20, 725–727 (news), 14 September 2021. The article page prints \"NEWS 14 September 2021\" and the citation \"Nature Reviews Drug Discovery 20, 725-727 (2021)\".","sourceIds":["source-aib-mullard-2021-nrdd"]},{"id":"aib-prop-predicted-structures-aid-drug-design","name":"Predicted protein structures aid drug design","type":"concept","proposition":{"code":"P1","criterion":"The text states that protein structures obtained by computational prediction, rather than by experiment, are or will be of use in designing or discovering drugs.","terms":["structure-based drug design"]}}],"claims":[{"id":"aib-arg-p1-mullard-2021","subject":"aib-doc-mullard-2021","predicate":"bears_on_proposition","object":{"kind":"entity","entityId":"aib-prop-predicted-structures-aid-drug-design"},"topic":"ideas","statement":"Mullard's Nature Reviews Drug Discovery news article \"What does AlphaFold mean for drug discovery?\" (14 September 2021) says in its standfirst that the implications of AlphaFold and RoseTTAFold for drug discovery are more incremental than their advance in structure prediction.","time":{"kind":"event","date":"2021-09-14","basis":"publication","note":"Date printed on the article page."},"derivation":"explicit","resolution":"supported","editorialState":"seed","evidenceIds":["evidence-aib-arg-p1-mullard-2021-1"],"attributes":{"thought":{"roles":["context"],"register":"nonfiction","missing":"Assesses the degree of the implications for drug discovery (\"more incremental\"); it does not state that predicted structures are of no use, nor that they are of use."}}}],"sources":[{"id":"source-aib-mullard-2021-nrdd","documentId":"aib-doc-mullard-2021","title":"What does AlphaFold mean for drug discovery?","authors":["Asher Mullard"],"publisher":"Nature Reviews Drug Discovery","publicationDate":"2021-09-14","version":"Retrieved for the candidate pack on 2026-10-30 (SHA-256 9e7115bb6c20032a92f104778da4e24a63f965e1731d2fe03d6428ce42acb2e9). Nature Reviews Drug Discovery news article page as served on 2026-10-30; standfirst and opening paragraph only, remainder behind subscription. Its wording can change; earlier wording is not authenticated.","evidenceUrl":"https://www.nature.com/articles/d41573-021-00161-0","language":"en"}],"evidence":[{"id":"evidence-aib-arg-p1-mullard-2021-1","claimId":"aib-arg-p1-mullard-2021","sourceId":"source-aib-mullard-2021-nrdd","sourceRole":"secondary","support":"supports","verification":"machine_checked","retrievalRoute":"direct"}],"at":{"entities":[1423,1442],"claims":[3726],"sources":[1212],"evidence":[5165]},"index":{"byClaim":[["aib-arg-p1-mullard-2021",["propositions:ai-in-science"]]],"marks":[],"chronicle":{"years":[{"year":1863,"topics":{"ideas":5},"stated":0},{"year":1865,"topics":{"ideas":1},"stated":0},{"year":1872,"topics":{"ideas":7},"stated":0},{"year":1943,"topics":{"ideas":1},"stated":0},{"year":1947,"topics":{"ideas":2},"stated":0},{"year":1950,"topics":{"ideas":7},"stated":0},{"year":1951,"topics":{"ideas":5},"stated":0},{"year":1952,"topics":{"ideas":2},"stated":0},{"year":1955,"topics":{"ideas":31},"stated":0},{"year":1956,"topics":{"ideas":1},"stated":0},{"year":1957,"topics":{"ideas":1},"stated":0},{"year":1958,"topics":{"ideas":3},"stated":0},{"year":1959,"topics":{"ideas":6},"stated":0},{"year":1960,"topics":{"ideas":11},"stated":0},{"year":1961,"topics":{"ideas":10},"stated":0},{"year":1965,"topics":{"ideas":8},"stated":0},{"year":1966,"topics":{"ideas":20},"stated":0},{"year":1968,"topics":{"ideas":5},"stated":0},{"year":1969,"topics":{"ideas":2},"stated":0},{"year":1971,"topics":{"ideas":4},"stated":0},{"year":1972,"topics":{"ideas":1},"stated":0},{"year":1973,"topics":{"ideas":2},"stated":0},{"year":1974,"topics":{"ideas":2},"stated":0},{"year":1975,"topics":{"ideas":1},"stated":0},{"year":1976,"topics":{"ideas":1},"stated":0},{"year":1977,"topics":{"people":2,"ideas":8},"stated":0},{"year":1979,"topics":{"ideas":4},"stated":0},{"year":1980,"topics":{"ideas":2},"stated":0},{"year":1981,"topics":{"people":2},"stated":0},{"year":1982,"topics":{"ideas":4},"stated":0},{"year":1983,"topics":{"ideas":4},"stated":0},{"year":1984,"topics":{"ideas":21},"stated":0},{"year":1985,"topics":{"ideas":9},"stated":0},{"year":1986,"topics":{"ideas":18},"stated":0},{"year":1987,"topics":{"ideas":1},"stated":0},{"year":1988,"topics":{"ideas":6},"stated":0},{"year":1989,"topics":{"ideas":8},"stated":0},{"year":1990,"topics":{"ideas":5},"stated":0},{"year":1991,"topics":{"ideas":11},"stated":0},{"year":1992,"topics":{"ideas":9},"stated":0},{"year":1993,"topics":{"ideas":14,"people":3},"stated":0},{"year":1994,"topics":{"ideas":14},"stated":0},{"year":1995,"topics":{"ideas":10,"people":1},"stated":0},{"year":1996,"topics":{"ideas":71},"stated":0},{"year":1997,"topics":{"ideas":12},"stated":0},{"year":1998,"topics":{"ideas":49},"stated":0},{"year":1999,"topics":{"ideas":27,"people":1,"institutions":1},"stated":0},{"year":2000,"topics":{"ideas":62},"stated":0},{"year":2001,"topics":{"ideas":39},"stated":0},{"year":2002,"topics":{"ideas":30},"stated":0},{"year":2003,"topics":{"ideas":8},"stated":0},{"year":2004,"topics":{"ideas":12,"people":3},"stated":0},{"year":2005,"topics":{"ideas":10,"people":1},"stated":0},{"year":2006,"topics":{"ideas":26,"people":1},"stated":0},{"year":2007,"topics":{"ideas":20},"stated":0},{"year":2008,"topics":{"ideas":57,"people":3,"institutions":1},"stated":0},{"year":2009,"topics":{"ideas":10,"people":1},"stated":0},{"year":2010,"topics":{"people":3,"ideas":11,"institutions":1,"governance":4},"stated":0},{"year":2011,"topics":{"people":3,"ideas":7,"institutions":2},"stated":0},{"year":2012,"topics":{"people":4,"ideas":17,"institutions":2},"stated":0},{"year":2013,"topics":{"ideas":46,"people":4,"institutions":2,"capital":1},"stated":0},{"year":2014,"topics":{"institutions":2,"ideas":54,"people":5},"stated":0},{"year":2015,"topics":{"people":22,"ideas":122,"institutions":3,"capital":1},"stated":0},{"year":2016,"topics":{"ideas":88,"people":2},"stated":0},{"year":2017,"topics":{"people":16,"institutions":2,"ideas":128,"governance":2},"stated":0},{"year":2018,"topics":{"people":8,"ideas":158,"institutions":8,"governance":1},"stated":0},{"year":2019,"topics":{"capital":1,"compute":1,"people":10,"governance":19,"ideas":175,"institutions":4},"stated":0},{"year":2020,"topics":{"people":6,"ideas":98,"institutions":1,"governance":2},"stated":0},{"year":2021,"topics":{"people":27,"ideas":177,"compute":1,"institutions":23,"governance":4,"capital":6},"stated":0},{"year":2022,"topics":{"people":15,"ideas":217,"institutions":6,"governance":3,"compute":2,"capital":1},"stated":0},{"year":2023,"topics":{"capital":5,"compute":7,"institutions":23,"people":51,"governance":179,"ideas":389},"stated":0},{"year":2024,"topics":{"capital":12,"compute":19,"governance":282,"people":80,"ideas":178,"institutions":28},"stated":1},{"year":2025,"topics":{"governance":547,"compute":69,"capital":34,"people":90,"institutions":18,"ideas":178},"stated":7},{"year":2026,"topics":{"governance":442,"capital":8,"compute":32,"institutions":21,"ideas":91,"people":107},"stated":19},{"year":2027,"topics":{},"stated":9},{"year":2028,"topics":{},"stated":6},{"year":2029,"topics":{},"stated":3},{"year":2030,"topics":{},"stated":3},{"year":2032,"topics":{},"stated":2},{"year":2035,"topics":{},"stated":2},{"year":2039,"topics":{},"stated":1},{"year":2042,"topics":{},"stated":1},{"year":2050,"topics":{},"stated":1}],"scheduled":[],"statedBy":[]},"collections":[{"target":{"kind":"propositions","id":"superintelligence"},"title":"Propositions about superintelligence, 1863–2022","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"risk-debate"},"title":"Arguments about catastrophic risk from advanced AI","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"yudkowsky-arguments"},"title":"Eliezer Yudkowsky’s arguments on common claims about AI, 1996–2026","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"economics-of-machine-intelligence"},"title":"Economics of machine intelligence","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"orbital-compute-arguments"},"title":"Arguments about compute in orbit","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"ai-bio-arguments"},"title":"Arguments about AI and biological risk","claimIds":[],"records":[]},{"target":{"kind":"propositions","id":"ai-in-science"},"title":"AI in science","claimIds":["aib-arg-p1-mullard-2021"],"records":[]},{"target":{"kind":"documents"},"title":"Frontier safety frameworks","claimIds":[]},{"target":{"kind":"compare","id":"frontier-safety-frameworks"},"title":"Compare frameworks","claimIds":[]},{"target":{"kind":"control","id":"openai"},"title":"OpenAI’s control structure, 2015–2026","claimIds":[]},{"target":{"kind":"control","id":"anthropic"},"title":"Anthropic’s control structure, 2021–2026","claimIds":[]},{"target":{"kind":"commitments"},"title":"External commitments and obligations","claimIds":[]},{"target":{"kind":"question","id":"frameworks-to-obligations"},"title":"Frameworks, commitments and legal obligations, 2023–2026","claimIds":[]},{"target":{"kind":"reading"},"title":"Founding and early leadership","claimIds":[]}]},"version":"131evrz"}