{"entities":[{"id":"igsc-harmonized-screening-protocol-v3-1","name":"IGSC Harmonized Screening Protocol v3.1","subtype":"Standard","description":"Version 3.1, dated 1 June 2026. Date on the first page ('1 June, 2026') and in the protocol's own revision table, which gives the same release date for v3.1.","sourceIds":["source-ab-igsc-hsp-v31"]},{"id":"igsc","name":"International Gene Synthesis Consortium"}],"claims":[{"id":"ab-scr-igsc-hsp-v31-published","statement":"The International Gene Synthesis Consortium published version 3.1 of its Harmonized Screening Protocol, dated 1 June 2026, which states that it sets out the standards and practices that the consortium's provider and manufacturer members apply to prevent the misuse of synthetic nucleic acids.","derivation":"explicit","resolution":"supported","editorialState":"seed","evidenceIds":["evidence-ab-scr-igsc-hsp-v31-published-1","evidence-ab-scr-igsc-hsp-v31-published-2"]},{"id":"ab-scr-igsc-hsp-v31-record-retention","statement":"Version 3.1 of the Harmonized Screening Protocol states that members retain records of every gene synthesised and delivered for a minimum of eight years after shipping, including the recipient's identity and shipping address, and retain every sequence screening result for at least eight years.","resolution":"supported","evidenceIds":["evidence-ab-scr-igsc-hsp-v31-record-retention-1","evidence-ab-scr-igsc-hsp-v31-record-retention-2"],"attributes":{"provision":{"kind":"required_action","key":"igsc-harmonized-screening-protocol-record-retention"}}},{"id":"ab-scr-igsc-hsp-v31-refusal-reporting","statement":"Version 3.1 of the Harmonized Screening Protocol states that members reserve the right to refuse to fill any order and to notify other members, law enforcement or other authorities on identifying potentially problematic orders, and that a reporting duty applies to requests within a category of sequences the protocol defines, received from a suspicious potential customer or from one that fails to establish legitimacy under the protocol’s customer-screening practices.","resolution":"supported","evidenceIds":["evidence-ab-scr-igsc-hsp-v31-refusal-reporting-1","evidence-ab-scr-igsc-hsp-v31-refusal-reporting-2"],"attributes":{"provision":{"kind":"required_action","key":"igsc-harmonized-screening-protocol-refusal-reporting"}}},{"id":"ab-scr-igsc-hsp-v31-screening-validation","statement":"Version 3.1 of the Harmonized Screening Protocol states that member companies regularly evaluate the efficacy of their automated sequence screening using a test set supplied by a source of standards recognised by the consortium, and that these evaluations are performed at least once every twelve months.","resolution":"supported","evidenceIds":["evidence-ab-scr-igsc-hsp-v31-screening-validation-1","evidence-ab-scr-igsc-hsp-v31-screening-validation-2"],"attributes":{"provision":{"kind":"required_action","key":"igsc-harmonized-screening-protocol-screening-validation"}}}],"sources":[{"id":"source-ab-igsc-hsp-v31","title":"IGSC Harmonized Screening Protocol v3.1","authors":["International Gene Synthesis Consortium (genesynthesisconsortium.org)"],"publisher":"International Gene Synthesis Consortium (genesynthesisconsortium.org)","publicationDate":null,"version":"Retrieved for the candidate pack on 2026-10-28 (SHA-256 9f6ea4906da571f0fae88e6b24f3b68dfe485ff19b88f849882ebe56f03a2fd3). Version 3.1, dated 1 June 2026 on its first page, as served on 2026-10-28. Its screening-data and methodology sections (sections 6 and the appendices) were read but are not cited. Retrieved again at admission on 2026-10-30 (SHA-256 9f6ea4906da571f0fae88e6b24f3b68dfe485ff19b88f849882ebe56f03a2fd3, the same bytes).","evidenceUrl":"https://genesynthesisconsortium.org/wp-content/uploads/IGSC-Harmonized-Screening-Protocol-V3.1.pdf","language":"en"}],"evidence":[{"id":"evidence-ab-scr-igsc-hsp-v31-published-1","sourceRole":"primary","support":"supports","verification":"machine_checked","retrievalRoute":"direct"},{"id":"evidence-ab-scr-igsc-hsp-v31-published-2","support":"supports","verification":"machine_checked","retrievalRoute":"direct"},{"id":"evidence-ab-scr-igsc-hsp-v31-record-retention-1","support":"supports","locator":"7.3 Record Keeping and Retention, requirement 3.1, p. 15","passage":"IGSC members retain records of every gene synthesized and delivered for a minimum of 8 years after shipping","passageType":"quote"},{"id":"evidence-ab-scr-igsc-hsp-v31-refusal-reporting-1","support":"supports","locator":"7.4 Order Refusal and Reporting, requirement 4.1, p. 15","passage":"IGSC members reserve the right to refuse to fill any order and to notify other IGSC members and/or law enforcement or other authorities upon identifying potentially problematic orders.","passageType":"quote"},{"id":"evidence-ab-scr-igsc-hsp-v31-screening-validation-1","support":"supports","locator":"7.2 Sequence Screening, requirement 2.6, PDF p. 14","passage":"IGSC companies regularly evaluate the efficacy of their automated sequence screening","passageType":"quote"}],"at":{"entities":[1206,1227],"claims":[3319,3320,3321,3322],"sources":[1050],"evidence":[4557,4558,4559,4561,4563]},"version":"1lg47t7"}