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The Framework states that it applies to federally funded life sciences research involving the procurement of all types of synthetic nucleic acids that contain a synthetic sequence within the category the framework defines, and of any benchtop equipment capable of synthesising nucleic acids, and to distribution by providers including biofoundries, cloud laboratories, institutions with core synthesis facilities and contract research organisations, and by manufacturers of benchtop equipment. Copy claim link
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Machine-checked, not reviewed by an editor Stated in source Supported
Supporting evidence: primary · 1 source
Provision Threshold or trigger · provision ID us-ostp-nucleic-acid-framework-scope Subject version The copy served from the Biden White House archive, marked 'Revised: September 2024' with '2024 Version 1: April 2024' · Published 2024-04-29 · Effective date not established · Revised 2024-09 Date 2024-09 · revision Scope and limits States the framework's stated scope. Whether a named company or institution falls in a category is not recorded, and the framework's qualifier that it covers acids containing a sequence of its defined category is reproduced only in that generality. The provision kind is `threshold`, the dataset’s kind for a provision that decides what is covered; the schema has no `definition` kind. That limitation was restored to the statement and to the paraphrase at admission, at policy level (cross-family check, item 68). The framework's definition of the sequences in scope is a technical screening criterion and is not recorded.
The evidence 02 primary source Supports the claim
Framework for Nucleic Acid Synthesis Screening (National Science and Technology Council, Fast Track Action Committee on Synthetic Nucleic Acid Procurement Screening) ↗ Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive) · Publication date unknown
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Source excerpt “This framework applies to federally funded life sciences research involving the procurement of all types of synthetic nucleic acids” Location in source III. Scope, p. 5
How it was read Retrieved directly from the publisher
Machine-checked · 2026-10-30
Source details and check notes Authors Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive) Version Retrieved for the candidate pack on 2026-10-28 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715). The copy linked from the HHS ASPR page on 2026-10-28, marked on its cover 'Revised: September 2024' with '2024 Version 1: April 2024'. The April 2024 version 1 was not retrieved. Technical passages (screening windows, matching methods, the criteria that may inform which sequences are in scope) were read but are not cited. Retrieved again at admission on 2026-10-30 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715, the same bytes). Canonical address Open the canonical source ↗ Accessed 2026-10-28 Language English (en) Attribution Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive), “Framework for Nucleic Acid Synthesis Screening (National Science and Technology Council, Fast Track Action Committee on Synthetic Nucleic Acid Procurement Screening)”. Reuse No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution. Check notes Candidate pack passage, AI and biosecurity (research/ai-bio). The quotation (19 words) matched the text retrieved for the candidate pack on 2026-10-28 and again at admission on 2026-10-30, in a fresh retrieval whose SHA-256 equals the pack’s. Matching ignored differences of whitespace, case, quotation marks, dashes and Unicode compatibility forms, so the source’s typography can differ. The sentence continues with examples of nucleic acid types and the qualifier that they contain a synthetic sequence of the framework's defined category. A cross-family machine check (2026-10-30, item 68) re-read the record’s sources and found partial support; its corrections were applied at admission. No human editorial review. primary source Supports the claim
Framework for Nucleic Acid Synthesis Screening (National Science and Technology Council, Fast Track Action Committee on Synthetic Nucleic Acid Procurement Screening) ↗ Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive) · Publication date unknown
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Paraphrase the framework also applies to federally funded life sciences research procuring any benchtop equipment capable of synthesising nucleic acids, and to distribution by providers, among them biofoundries, cloud labs, institutions with core nucleic acid synthesis facilities and contract research organisations, and by manufacturers of benchtop equipment; the scope sentence limits the nucleic acids covered to those containing a synthetic sequence of the framework’s defined category.
Location in source III. Scope, p. 5
How it was read Retrieved directly from the publisher
Machine-checked · 2026-10-30
Source details and check notes Authors Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive) Version Retrieved for the candidate pack on 2026-10-28 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715). The copy linked from the HHS ASPR page on 2026-10-28, marked on its cover 'Revised: September 2024' with '2024 Version 1: April 2024'. The April 2024 version 1 was not retrieved. Technical passages (screening windows, matching methods, the criteria that may inform which sequences are in scope) were read but are not cited. Retrieved again at admission on 2026-10-30 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715, the same bytes). Canonical address Open the canonical source ↗ Accessed 2026-10-28 Language English (en) Attribution Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive), “Framework for Nucleic Acid Synthesis Screening (National Science and Technology Council, Fast Track Action Committee on Synthetic Nucleic Acid Procurement Screening)”. Reuse No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution. Check notes Candidate pack passage, AI and biosecurity (research/ai-bio). The paraphrase is Selekoa’s, written from the text retrieved for the candidate pack on 2026-10-28; it is not a quotation and was not machine-matched. The paraphrase was widened at admission to carry the scope limitation the quoted fragment leaves out, at policy level and without the framework’s definition of the category (cross-family check, item 68). A cross-family machine check (2026-10-30, item 68) re-read the record’s sources and found partial support; its corrections were applied at admission. No human editorial review. Status and meaning Editorial status. Not reviewed by an editor . An exploratory record that no editor has accepted. This status does not say whether a person has read any linked passage. Each evidence record above shows how it was checked.
Relation. An exact framework edition, or another document with an exact expression, states one provision: a capability threshold or risk level and its trigger, a required safeguard or action, a decision authority (who decides, recommends, can overrule or is informed), a stated exception, or another statement of its content, such as a licence term or a prospectus statement. The passage records what the document says, not implementation, compliance or effectiveness. Provisions with the same key align across editions of one family.
Date. Provision as the text states it, dated by its date of revision, September 2024. Release date 29 April 2024 from the HHS ASPR page, which also gives 'revised September 2024'; the cover of the retrieved copy carries 'Revised: September 2024' and '2024 Version 1: April 2024'. The day of the September 2024 revision is not stated and stays unknown. The framework's own effective date for the funding requirement, 26 April 2025, is recorded as a claim.
Record ID ab-scr-ostp-framework-scope