Framework for Nucleic Acid Synthesis Screening
The copy served from the Biden White House archive, marked 'Revised: September 2024' with '2024 Version 1: April 2024'. Release date 29 April 2024 from the HHS ASPR page, which also gives 'revised September 2024'; the cover of the retrieved copy carries 'Revised: September 2024' and '2024 Version 1: April 2024'. The day of the September 2024 revision is not stated and stays unknown. The framework's own effective date for the funding requirement, 26 April 2025, is recorded as a claim.
- Issued by
- Office of Science and Technology Policy (Executive Office of the President)
- Authors credited
- No authorship claim recorded yet. The source record lists Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive).
- Dates
- Published 2024-04-29 issue evidence
- Revised 2024-09
Release date 29 April 2024 from the HHS ASPR page, which also gives 'revised September 2024'; the cover of the retrieved copy carries 'Revised: September 2024' and '2024 Version 1: April 2024'. The day of the September 2024 revision is not stated and stays unknown. The framework's own effective date for the funding requirement, 26 April 2025, is recorded as a claim.
- Exact source
- Framework for Nucleic Acid Synthesis Screening (National Science and Technology Council, Fast Track Action Committee on Synthetic Nucleic Acid Procurement Screening) Office of Science and Technology Policy, Executive Office of the President (copy served from the Biden White House archive) · publication date unknown · Retrieved for the candidate pack on 2026-10-28 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715). The copy linked from the HHS ASPR page on 2026-10-28, marked on its cover 'Revised: September 2024' with '2024 Version 1: April 2024'. The April 2024 version 1 was not retrieved. Technical passages (screening windows, matching methods, the criteria that may inform which sequences are in scope) were read but are not cited. Retrieved again at admission on 2026-10-30 (SHA-256 3b083af856f92dfa91bbf5de344ca81761a4eb4c3a0323fa390e37330a802715, the same bytes).
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Versions
us-ostp-nucleic-acid-synthesis-screening-framework: 1 recorded version, oldest first, published by Office of Science and Technology Policy (Executive Office of the President). A version is shown as replacing another only where a record says so. Date order alone never implies it.
- 2024-09 · revisedThe copy served from the Biden White House archive, marked 'Revised: September 2024' with '2024 Version 1: April 2024' (this version)
This version
Provisions in this version · 5 quoted
A limited selection of quoted provisions: what this edition says about thresholds, required actions, who decides and exceptions, and other statements of the text. It is not a full summary and says nothing about implementation. A “not found” record states which part of the edition was inspected. It is not a claim that the text was deleted.
- Threshold or triggerScope: federally funded life sciences research procurement, and the providers and manufacturers whose distribution is covered“This framework applies to federally funded life sciences research involving the procurement of all types of synthetic nucleic acids”III. Scope, p. 5Inspect claim & evidence ↗
- Required actionAttestation criterion for adherence (criterion 1), with signature, contact, annual update and 72-hour notification“either post on a public webpage a statement that self-attests to following each of the criteria in this framework, or provide such a statement to the federally funded customer and the federal funding agency upon request”V. Screening Framework, criterion 1, p. 8Inspect claim & evidence ↗
- Required actionInteragency review before 13 October 2026 and recurring review of the framework“an OSTP-designated interagency group will assess the scientific state of the art before October 13, 2026 and recommend any updates to this framework if necessary”V. Screening Framework, criterion 2, PDF p. 11 (printed p. 10)Inspect claim & evidence ↗
- ExceptionCase-by-case exceptions by heads of federal funding agencies“The heads of federal funding agencies may issue exceptions to the requirements in this framework on a case-by-case basis when needed to address health or national security priorities, in consultation with the Director of OSTP and the Federal Bureau of Investigation.”II. Role of Federal Funding Agencies, p. 5Inspect claim & evidence ↗
- Stated dateDate from which the funding requirement applies to purchases (26 April 2025)“This requirement will take effect for all purchases of synthetic nucleic acids and benchtop nucleic synthesis equipment that take place on or after April 26, 2025.”II. Role of Federal Funding Agencies, p. 5Inspect claim & evidence ↗
Earliest version recorded here; no replacement is recorded.
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