Claim · 2024-05-08 · publication · Stated in source · Supported

Abramson et al. (Nature, 8 May 2024) state in their section on model limitations that they still observe a chirality violation rate of 4.4% in the benchmark.

One recorded claim. The claim panel gives its qualification, the source passages with their place in each source, and how it was checked.

What it connects

Accurate structure prediction of biomolecular interactions with AlphaFold 3 → states provision → Stated limit: chirality violations at a rate of 4.4% in the benchmark

Where it appears

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Claim and evidence

Accurate structure prediction of biomolecular interactions with AlphaFold 3states provision ↓Stated limit: chirality violations at a rate of 4.4% in the benchmark

Machine-checked, not reviewed by an editorStated in sourceSupported

Supporting evidence: primary · 1 source

Provision: Statement · provision ID mod-af3-chirality-limit
Date: 2024-05-08 · publication Records dated 2024 →

Scope and limitsA limitation the authors state for one benchmark set; the figure is theirs and is not independently verified.

The evidence 01

primary sourceSupports the claim

Accurate structure prediction of biomolecular interactions with AlphaFold 3

Nature · 2024-05-08

Cite the original source

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Source excerpt

“Despite this, we still observe a chirality violation rate of 4.4% in the benchmark.”

Location in source "Model limitations" section

How it was read Retrieved directly from the publisher

Machine-checked · 2026-10-30

Source details and check notes

Authors: Josh Abramson; Jonas Adler; Jack Dunger; Richard Evans; Tim Green; Alexander Pritzel; Olaf Ronneberger; Lindsay Willmore; Andrew J. Ballard; Joshua Bambrick; Sebastian W. Bodenstein; David A. Evans; Chia-Chun Hung; Michael O’Neill; David Reiman; Kathryn Tunyasuvunakool; Zachary Wu; Akvilė Žemgulytė; Eirini Arvaniti; Charles Beattie; Ottavia Bertolli; Alex Bridgland; Alexey Cherepanov; Miles Congreve; Alexander I. Cowen-Rivers; Andrew Cowie; Michael Figurnov; Fabian B. Fuchs; Hannah Gladman; Rishub Jain; Yousuf A. Khan; Caroline M. R. Low; Kuba Perlin; Anna Potapenko; Pascal Savy; Sukhdeep Singh; Adrian Stecula; Ashok Thillaisundaram; Catherine Tong; Sergei Yakneen; Ellen D. Zhong; Michal Zielinski; Augustin Žídek; Victor Bapst; Pushmeet Kohli; Max Jaderberg; Demis Hassabis; John M. Jumper
Version: Retrieved for the candidate pack on 2026-10-30 (SHA-256 6b48f4d09ceeaa4fceb473e37dbc7789b2a5e57633ca7b200aaa4646e4eac657). Nature article page (open access), as served on 2026-10-30 (the page notes an addendum of 27 November 2024); author list and Author information section. The candidate pack retrieved the same page a second time on 2026-10-30, at an address carrying a cookie-error query string (SHA-256 40b72aa72d12e37e9b6df5a3ebad23bfcb68a9c2c4db79a7df9b2ad76231b1c3); the passages read in that retrieval are cited here.
Canonical address: Open the canonical source ↗
Accessed: 2026-10-30
Language: English (en)
Attribution: Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Alexander Pritzel, Olaf Ronneberger, Lindsay Willmore, Andrew J. Ballard, Joshua Bambrick, Sebastian W. Bodenstein, David A. Evans, Chia-Chun Hung, Michael O’Neill, David Reiman, Kathryn Tunyasuvunakool, Zachary Wu, Akvilė Žemgulytė, Eirini Arvaniti, Charles Beattie, Ottavia Bertolli, Alex Bridgland, Alexey Cherepanov, Miles Congreve, Alexander I. Cowen-Rivers, Andrew Cowie, Michael Figurnov, Fabian B. Fuchs, Hannah Gladman, Rishub Jain, Yousuf A. Khan, Caroline M. R. Low, Kuba Perlin, Anna Potapenko, Pascal Savy, Sukhdeep Singh, Adrian Stecula, Ashok Thillaisundaram, Catherine Tong, Sergei Yakneen, Ellen D. Zhong, Michal Zielinski, Augustin Žídek, Victor Bapst, Pushmeet Kohli, Max Jaderberg, Demis Hassabis, John M. Jumper, “Accurate structure prediction of biomolecular interactions with AlphaFold 3”, 2024-05-08.
Reuse: No open redistribution licence asserted. Bibliographic metadata, editorial paraphrases and short attributed quotations (at most 50 words each). Recheck terms before wider redistribution.
Check notes: Candidate pack passage, AI in biology (research/ai-in-biology). The quotation (14 words) matched the text retrieved for the candidate pack on 2026-10-30. Matching ignored differences of whitespace, case, quotation marks, dashes and Unicode compatibility forms, so the source’s typography can differ. No human editorial review.

Status and meaning

Editorial status. Not reviewed by an editor. An exploratory record that no editor has accepted. This status does not say whether a person has read any linked passage. Each evidence record above shows how it was checked.

Relation. An exact framework edition, or another document with an exact expression, states one provision: a capability threshold or risk level and its trigger, a required safeguard or action, a decision authority (who decides, recommends, can overrule or is informed), a stated exception, or another statement of its content, such as a licence term or a prospectus statement. The passage records what the document says, not implementation, compliance or effectiveness. Provisions with the same key align across editions of one family.

Date. Date of the paper stating the limitation.

Record ID aib-mod-af3-chirality-limit